Apparently AI under the control of a rogue actor is undoubtedly going to kill us all with a synthesized virus.
Let me run you through how brain rotted the world is now that this is even being taken in the slightest seriousness.
You cant just prompt an AI model, hey make me a humanity ending virus, no mistakes and send it to the printers. That’s not how reality works. To generate a world ending virus. You will need the following chain of events. If each one fails, the whole chain of events fail.
Step A: AI generates a viable novel pathogen sequence.
Highly unlikely without massive human intervention and iterative wet-lab feedback. Let’s say 1% chance for a non-expert using public tools.
Step B: The sequence is stable enough to be synthesized and remain infectious.
Many generated sequences are nonsense or unstable. Probability of viability: 5%.
Step C: It bypasses DNA synthesis screening (Know-Your-Customer rules).
Screening is imperfect but effective against known dangerous motifs. Probability: 10%.
Step D: The actor has access to a BSL-3/4 lab capable of handling high-consequence pathogens.
You forget extensive of testing of the novel virus canidates is needed so you can validate the virus’s virality. You can’t do this in a garage. You need specialized infrastructure, containment, waste disposal, and ethical blind spots. Probability for a random bad actor: <0.1%.
Step E: The virus achieves optimal transmissibility AND lethality simultaneously.
Biologically, these often trade off. High lethality usually kills the host before they spread it widely. Finding the “sweet spot” is incredibly hard. Probability: 1%.
Step F: It spreads globally before detection/response.
Modern surveillance, travel restrictions, and medical response are faster than in 1918 or 2020. Probability of total global saturation before countermeasures: 5%.
Any one of these fail and you dont get an outbreak.
Total Probability:
0.01 ×0.05 ×0.10 ×0.001 ×0.01 ×0.05 =0.00000000000025%
And before you say state actor will do this. They already can if they want to.


Maybe, maybe not. Given LLMs’ success in certain molecular research, like protein folding, I’d guess (see how easily it is to not pretend that making shit up is authoritative?) that the probability isn’t zero. I certainly don’t trust tech CEOs, though.
you sir are an idiot, you just made up non zero probability ROFLMAO mate you are brain rotted. keep on shilling man
And I labeled it as a guess, and my error bars are nearly the entire probability space. I didn’t just make up a bunch of numbers and pretend that they were authoritative.
I literally would not have replied to your initial post at all if you had just listed the obstacles instead of making up numbers and pretending that they meant anything.